TAP1 antibody

GeneTex

TAP1 antibody

9

ICC: Use at an assay dependent dilution. IP: Use at a dilution of 1/100. WB: Use at a dilution of 1/4000. Detects a band of approximately 70 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

TAP1

transporter 1, ATP binding cassette subfamily B member

ABC transporter, MHC 1; ABC17; ABCB2; antigen peptide transporter 1; APT1; ATP-binding cassette sub-family B member 2; ATP-binding cassette, sub-family B (MDR/TAP), member 2; D6S114E; peptide supply factor 1; peptide transporter involved in antigen processing 1; peptide transporter PSF1; peptide transporter TAP1; PSF1; PSF-1; really interesting new gene 4 protein; RING4; TAP1*0102N; TAP1N; transporter 1 ATP-binding cassette sub-family B; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP); transporter associated with antigen processing; transporter, ATP-binding cassette, major histocompatibility complex, 1

Rabbit

IgG

Antigen peptide transporter 1

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Human, Rat

-20°C or -80°C,2°C to 8°C

12352203