TAPI-0 [163958-73-4]

MedChem Express

TAPI-0 [163958-73-4]

10

163958-73-4

Research Use Only

98.98

C24H32N4O5

456.53

TAPI-0 is a TACE (TNF-alpha converting enzyme; ADAM17) inhibitor with an IC50 of 100 nM. TAPI-0 is a MMP inhibitor and also attenuates TNF-alpha processing[1][2].

ONC(C[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)CC1=CC2=C(C=C1)C=CC=C2)=O)CC(C)C)=O

-20°C,-80°C

12352200