
Western Blot Positive WB detected in: K562 whole cell lysate, A549 whole cell lysate, Hela whole cell lysate, HL60 whole cell lyasate, MCF-7 whole cell lysate, HepG2 whole cell lysate, SH-SY5Y whole cell lysate All lanes: TARDBP antibody at 2.5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45, 32 kDa Observed band size: 45 kDa
TARDBP Antibody

CSB-PA023129EA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTARDBP
Overview
- SupplierCusabio
- Product NameTARDBP Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID23435
- Target nameTARDBP
- Target descriptionTAR DNA binding protein
- Target synonymsALS10; TAR DNA-binding protein 43; TAR DNA-binding protein-43; TDP-43
- HostRabbit
- IsotypeIgG
- Protein IDQ13148
- Protein NameTAR DNA-binding protein 43
- Scientific DescriptionDNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3\\\-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3\\\ UTR.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203