TAS-117 hydrochloride

TargetMol Chemicals

TAS-117 hydrochloride

10

Research Use Only

TAS-117 hydrochloride

C26H25ClN4O2

460.96

TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM). TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can induce apoptosis and autophagy.

3 years

-20°C

12352200