Overview
- SupplierTargetMol Chemicals
- Product NameTAT-MEK1 [566872-16-0]
- Delivery Days Customer16
- CertificationResearch Use Only
- Molecular FormulaC136H241N53O31S
- Molecular Weight3146.77
- Scientific DescriptionTAT-MEK1, an inhibitor of ERK2, comprises TAT and MEK1 (N-terminal). The TAT component (YGRKKRRQRRR) is a cell-penetrating peptide derived from the human immunodeficiency (HIV-1) transcriptional trans activator (TAT). TAT-MEK1 has an IC50 of 29 microM for ERK2 in vitro [1] [2].
- SMILESC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)NC(CN)=O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCSC)=O)CCC1)CCCCN)=O)CCCCN)=O)CCCCN)(=O)N3[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(N)=O)CCC5)CC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCC4)[C@@H](C)O)=O)CCC3
- Storage Instruction-20°C
- UNSPSC12352200