TBA-7371
HY-19750
CAS Number1494675-86-3
Product group Chemicals
Estimated Purity99.91
Molecular Weight355.39
Overview
- SupplierMedChem Express
- Product NameTBA-7371 [1494675-86-3]
- Delivery Days Customer10
- CAS Number1494675-86-3
- CertificationResearch Use Only
- Estimated Purity99.91
- Molecular FormulaC18H21N5O3
- Molecular Weight355.39
- Scientific DescriptionTBA-7371 is an orally active and non-covalent inhibitor of Decaprenylphosphoryl-beta-D-ribose oxidase (DprE1) of Mycobacterium tuberculosis (MIC=0.64 microg/mL). TBA-7371 can block the synthesis of arabinose in the bacterial cell wall, resulting in cell wall structural defects, thereby exerting an anti-tuberculosis effect. TBA-7371 can be used in the research of anti-tuberculosis drugs and has a synergistic bactericidal effect with Bedaquiline (HY-14881) and other drugs[1][2][3].
- SMILESO=C(C1=CN(CC2=NC=NC(OC)=C2C)C3=CC(C)=CN=C31)NCCO
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200