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ProductsBack/TBB [17374-26-4]
Chemical Structure
Chemical Structure
Chemical Structure

TBB [17374-26-4]

Research Use Only
AG-CR1-3660
AdipoGen Life Sciences
CAS Number17374-26-4
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight434.7
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    TBB
  • Delivery Days Customer
    10
  • CAS Number
    17374-26-4
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C6HBr4N3
  • Molecular Weight
    434.7
  • Scientific Description
    ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor (IC50=0.9microM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase (IC50=15.6, 11.2 and 8.7microM, respectively). Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP. Moderate DYRK1A inhibitor (IC50=4.4microM). Induces caspase-dependent apoptosis and degrades hematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. - Chemical. CAS: 17374-26-4. Formula: C6HBr4N3. MW: 434.7. Synthetic. ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor (IC50=0.9microM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase (IC50=15.6, 11.2 and 8.7microM, respectively). Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP. Moderate DYRK1A inhibitor (IC50=4.4microM). Induces caspase-dependent apoptosis and degrades hematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
  • SMILES
    BrC1=C(Br)C(Br)=C(Br)C2=C1N=NN2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51202000