WB analysis of (A) 293 and (B) Daudi cell lysate using GTX85437 TBC1D1 antibody. Working concentration : 2 microg/ml
WB analysis of (A) 293 and (B) Daudi cell lysate using GTX85437 TBC1D1 antibody. Working concentration : 2 microg/ml
TBC1D1 antibody
GTX85437
Overview
- SupplierGeneTex
- Product NameTBC1D1 antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody is specific for TBC1D1 C-Terminus
- Application Supplier NoteWB: 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID23216
- Target nameTBC1D1
- Target descriptionTBC1 domain family member 1
- Target synonymsTBC; TBC1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1
- Protein IDQ86TI0
- Protein NameTBC1 domain family member 1
- Scientific DescriptionTBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203