Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA873720LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA873720LA01HU at dilution of 1:100
TBC1D7 Antibody
CSB-PA873720LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTBC1D7
Overview
- SupplierCusabio
- Product NameTBC1D7 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID51256
- Target nameTBC1D7
- Target descriptionTBC1 domain family member 7
- Target synonymscell migration-inducing protein 23; MGCPH; PIG51; TBC1 domain family member 7; TBC7; TS complex subunit 3
- HostRabbit
- IsotypeIgG
- Protein IDQ9P0N9
- Protein NameTBC1 domain family member 7
- Scientific DescriptionComponent of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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