TBK1/IKKepsilon-IN-4

MedChem Express

TBK1/IKKepsilon-IN-4 [1381930-17-1]

10

1381930-17-1

Research Use Only

99.42

C28H35N7O4

533.62

TBK1/IKKepsilon-IN-4 is a 6-aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKKepsilon inhibitor with IC 50 values of 13 nM and 59 nM, respectively. TBK1/IKKepsilon-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family members and mTOR [1] .

COC1=CC=C(N2N=CC3=CN=C(NC4=CC(OCCCN5CCN(C)CC5)=C(OC)C(OC)=C4)N=C32)C=C1

2°C to 8°C

12352200