TBK1/IKKepsilon-IN-4 [1381930-17-1]

TargetMol Chemicals

TBK1/IKKepsilon-IN-4 [1381930-17-1]

72

1381930-17-1

Chemical

Research Use Only

TBK1/IKKepsilon-IN-4

C28H35N7O4

533.62

TBK1/IKKepsilon-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKepsilon, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced activity, by 100- to 1000-fold, against other protein kinases, such as PDK1, PI3K family members, and mTOR[1].

3 years

COc1ccc(cc1)-n1ncc2cnc(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)nc12

-20°C

51202000