TBK1/IKKepsilon-IN-5
HY-128679
CAS Number1893397-65-3
Product group Chemicals
Estimated Purity99.23
Molecular Weight513.59
Overview
- SupplierMedChem Express
- Product NameTBK1/IKKepsilon-IN-5 [1893397-65-3]
- Delivery Days Customer10
- CAS Number1893397-65-3
- CertificationResearch Use Only
- Estimated Purity99.23
- Molecular FormulaC28H31N7O3
- Molecular Weight513.59
- Scientific DescriptionTBK1/IKKepsilon-IN-5 (compound 1) is an orally active TBK1 and IKKepsilon dual inhibitor, with IC50 values of 1 and 5.6 nM, respectively. TBK1/IKKepsilon-IN-5 enhances the blockade response to PD-1 and induces immune memory in rats when combines with anti-PD-L1. TBK1/IKKepsilon-IN-5 can be used in cancer research, especially in tumour immunity[1].
- SMILESN#CC1=CC(C2=NC(NC3=CC=C(N4CCN(C5COC5)CC4)C=C3)=NC=N2)=CC=C1OC6CCOCC6
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200