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TBK1/IKKepsilon-IN-5

HY-128679
MedChem Express
CAS Number1893397-65-3
Product group Chemicals
Estimated Purity99.23
Molecular Weight513.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TBK1/IKKepsilon-IN-5 [1893397-65-3]
  • Delivery Days Customer
    10
  • CAS Number
    1893397-65-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.23
  • Molecular Formula
    C28H31N7O3
  • Molecular Weight
    513.59
  • Scientific Description
    TBK1/IKKepsilon-IN-5 (compound 1) is an orally active TBK1 and IKKepsilon dual inhibitor, with IC50 values of 1 and 5.6 nM, respectively. TBK1/IKKepsilon-IN-5 enhances the blockade response to PD-1 and induces immune memory in rats when combines with anti-PD-L1. TBK1/IKKepsilon-IN-5 can be used in cancer research, especially in tumour immunity[1].
  • SMILES
    N#CC1=CC(C2=NC(NC3=CC=C(N4CCN(C5COC5)CC4)C=C3)=NC=N2)=CC=C1OC6CCOCC6
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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