TBL1X antibody [C3], C-term
GTX107736
Overview
- SupplierGeneTex
- Product NameTBL1X antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.94 mg/ml
- ConjugateUnconjugated
- Gene ID6907
- Target nameTBL1X
- Target descriptiontransducin beta like 1 X-linked
- Target synonymsCHNG8; EBI; F-box-like/WD repeat-containing protein TBL1X; SMAP55; TBL1; transducin beta like 1X-linked; transducin beta-like protein 1X; transducin-beta-like protein 1, X-linked
- HostRabbit
- IsotypeIgG
- Protein IDO60907
- Protein NameF-box-like/WD repeat-containing protein TBL1X
- Scientific DescriptionThe protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Transducin beta-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma. Youssef Y et al., 2021 Nov 1, HaematologicaRead more