TBPB [634616-95-8]
HY-14562
CAS Number634616-95-8
Product group Chemicals
Estimated Purity99.74
Molecular Weight404.55
Overview
- SupplierMedChem Express
- Product NameTBPB [634616-95-8]
- Delivery Days Customer10
- CAS Number634616-95-8
- CertificationResearch Use Only
- Estimated Purity99.74
- Molecular FormulaC25H32N4O
- Molecular Weight404.55
- Scientific DescriptionTBPB (tert-butyl peroxybenzoate) is a highly selective, blood-brain-permeable M1 mAChR allosteric agonist (EC50=289 nM) with anti-schizophrenia and anti-inflammatory activities. TBPB can enhance the sensitivity of M1 receptors to acetylcholine, activate downstream signaling pathways, and inhibit the release of pro-inflammatory cytokines (TNF-alpha, IL-6). TBPB can regulate the processing of amyloid and can be used in the study of neurodegenerative diseases (such as Alzheimers disease) and inflammation-related diseases (such as sepsis)[1][2][3].
- SMILESO=C1N(C2CCN(C3CCN(CC4=C(C)C=CC=C4)CC3)CC2)C5=CC=CC=C5N1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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