TBX1 antibody

GeneTex

TBX1 antibody

9

WB: 1:500~1:1000. ICC/IF: 1:100~1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

TBX1

T-box transcription factor 1

brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; T-box 1 transcription factor C; T-box transcription factor TBX1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS

Rabbit

IgG

T-box transcription factor TBX1

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203