TBX21 blocking peptide

GeneTex

TBX21 blocking peptide

9

Neutralisation/Blocking

Research Use Only

200 ug/ml

Unconjugated

TBX21

T-box transcription factor 21

IMD88, T-PET, T-bet, TBET, TBLYM, T-box transcription factor TBX21, T-box 21, T-box expressed in T cells, T-box protein 21, T-box transcription factor expressed in T cells, T-cell-specific T-box transcription factor T-bet, transcription factor TBLYM

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]

-20°C

41116100

Human