TC ASK 10

MedChem Express

TC ASK 10 [1005775-56-3]

10

1005775-56-3

Research Use Only

99.84

C21H23Cl2N5O

432.35

TC ASK 10 (Compound 10) is a potent, selective and orally active apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 of 14 nM. The inhibitory activities of TC ASK 10 towards other representative panel of kinases are less than 50%, except for ASK2 (IC50 of 0.51 microM)[1].

O=C(NC1=CN2C=C(N3C=CN=C3)C=CC2=N1)C4=CC=C(C(C)(C)C)C=C4.[H]Cl.[H]Cl

2°C to 8°C

12352200