TC-E 5001 [865565-29-3]

MedChem Express

TC-E 5001 [865565-29-3]

10

865565-29-3

Research Use Only

C20H19N5O3S

409.46

TC-E 5001 is an inhibitor of Wnt pathway that inhibits tankyrase 1/2 (TNKS1/2) via novel adenosine pocket binding, with Kds of 79 nM and 28 nM, respectively. TC-E 5001 also inhibits Axin2 and STF, with IC50s of 0.709 microM and 0.215 microM, respectively[1][2].

CC1=NN=C(SCC2=NC(C3=CC=C(OC)C=C3)=NO2)N1C4=CC=C(OC)C=C4

12352200