TC-E 5005 [959705-64-7]

MedChem Express

TC-E 5005 [959705-64-7]

10

959705-64-7

Research Use Only

C15H18N4O

270.33

TC-E 5005 is a potent and selective PDE10A inhibitor with IC50 values of 7.28, 239, 779, 919, 3,100, and 3,700 nM for PDE10A, 2A, 11A, 5A, 7B and 3A, respectively. TC-E 5005 inhibits adrenergic and neurogenic smooth muscle contractions in the human prostate[1].

COC1=CC=C2C(N3C(C(C)=N2)=C(C)N=C3CCC)=N1

12352200