TC-I 15

MedChem Express

TC-I 15 [916734-43-5]

10

916734-43-5

Research Use Only

99.94

C23H28N4O6S2

520.62

TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin alpha2beta1 inhibitor, and it also inhibits alpha1beta1 and alpha11beta1 . TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, [1] [2] .

O=[S](N(CSC(C)1C)[C@@H]1C(N[C@H](C(O)=O)CNC(NCC2=CC=CC=C2)=O)=O)(C3=CC=CC=C3)=O

-20°C

12352200