TC-S 7009 [1422955-31-4]

TargetMol Chemicals

TC-S 7009

4

1422955-31-4

Chemical

Research Use Only

TC-S 7009

99.71%

C12H6ClFN4O3

308.65

TC-S 7009 is a potent and selective HIF-2alpha inhibitor (Kd: 81 nM) with significantly higher affinity for HIF-2alpha than HIF-1alpha (Kd >> 5microM). TC-S 7009 disrupts HIF-2alpha heterodimerization, reduces HIF-2alpha target gene expression, and diminishes DNA binding activity.

3 years

[O-][N+](=O)c1c(Nc2cc(F)cc(Cl)c2)ccc2nonc12

-20°C

12352200