TC-SP 14 [1257093-40-5]

MedChem Express

TC-SP 14 [1257093-40-5]

10

1257093-40-5

Research Use Only

C25H20F2N2O2S

450.50

TC-SP 14 (compound 14) is an orally active and potent S1P1 agonist (EC50 = 0.042 microM) with minimal activity at S1P3 (EC50 = 3.47 microM). TC-SP 14 significantly reduces blood lymphocyte counts and attenuates a delayed type hypersensitivity (DTH) response to antigen challenge[1].

O=C(C1CN(CC2=CC=C(C3=NC4=CC(CC5=CC=CC=C5F)=CC=C4S3)C(F)=C2)C1)O

12352200