
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA874804LA01HU at dilution of 1:100
TCHP Antibody
CSB-PA874804LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTCHP
Overview
- SupplierCusabio
- Product NameTCHP Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID84260
- Target nameTCHP
- Target descriptiontrichoplein keratin filament binding
- Target synonymsmitochondrial protein with oncostatic activity; mitostatin; TpMs; trichoplein keratin filament-binding protein; tumor suppressor protein
- HostRabbit
- IsotypeIgG
- Protein IDQ9BT92
- Protein NameTrichoplein keratin filament-binding protein
- Scientific DescriptionTumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a capping or branching protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161