
WB analysis of Jurkat cell lysate using GTX88906 TCL1A antibody, Internal. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
TCL1A antibody, Internal
GTX88906
Overview
- SupplierGeneTex
- Product NameTCL1A antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.1-0.3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID8115
- Target nameTCL1A
- Target descriptionTCL1 family AKT coactivator A
- Target synonymsoncogene TCL1; oncogene TCL-1; protein p14 TCL1; T cell leukemia/lymphoma 1A; T-cell leukemia/lymphoma protein 1A; T-cell lymphoma-1; TCL1
- HostGoat
- IsotypeIgG
- Protein IDP56279
- Protein NameT-cell leukemia/lymphoma protein 1A
- Scientific DescriptionOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203