TCO-PEG1-Val-Cit-PABC-PNP

MedChem Express

TCO-PEG1-Val-Cit-PABC-PNP

10

Research Use Only

C39H53N7O12

811.88

TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

O=C(NCCOCCC(N[C@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)=O)=O)=O)OC3C/C=C/CCCC3

41115800