
IHC-P analysis of mouse spinal cord tissue using GTX33536 TCP1 delta antibody. Dilution : 1:100
TCP1 delta antibody
GTX33536
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCCT4
Overview
- SupplierGeneTex
- Product NameTCP1 delta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10575
- Target nameCCT4
- Target descriptionchaperonin containing TCP1 subunit 4
- Target synonymsCCT-DELTA, Cctd, SRB, T-complex protein 1 subunit delta, TCP-1-delta, chaperonin containing T-complex polypeptide 1 subunit 4, chaperonin containing TCP1, subunit 4 (delta), chaperonin containing t-complex polypeptide 1, delta subunit, stimulator of TAR RNA-binding
- HostRabbit
- IsotypeIgG
- Protein IDP50991
- Protein NameT-complex protein 1 subunit delta
- Scientific DescriptionThe chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chang YX, Lin YF, Chen CL, et al. Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways. Cancers (Basel). 2020,12(12). doi: 10.3390/cancers12123865Read this paper






![Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with TCP1 delta antibody [N1C2] (GTX119638) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX119638/GTX119638_40527_20211203_WB_w_23060519_617.webp)


