Bio-Connect

TCS 21311 [1260181-14-3]

HY-108264
MedChem Express
CAS Number1260181-14-3
Product group Chemicals
Estimated Purity99.49
Molecular Weight526.51
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    TCS 21311 [1260181-14-3]
  • Delivery Days Customer
    10
  • CAS Number
    1260181-14-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.49
  • Molecular Formula
    C27H25F3N4O4
  • Molecular Weight
    526.51
  • Scientific Description
    TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC50 of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCalpha, PKCtheta, and GSK3beta with IC50s of 13, 68, and 3 nM, respectively[1].
  • SMILES
    O=C(C(C1=CC(N2CCN(C(C(C)(O)C)=O)CC2)=CC=C1C(F)(F)F)=C3C4=CNC5=C4C=CC=C5)NC3=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200