TCS 21311 [1260181-14-3]
HY-108264
CAS Number1260181-14-3
Product group Chemicals
Estimated Purity99.49
Molecular Weight526.51
Overview
- SupplierMedChem Express
- Product NameTCS 21311 [1260181-14-3]
- Delivery Days Customer10
- CAS Number1260181-14-3
- CertificationResearch Use Only
- Estimated Purity99.49
- Molecular FormulaC27H25F3N4O4
- Molecular Weight526.51
- Scientific DescriptionTCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC50 of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCalpha, PKCtheta, and GSK3beta with IC50s of 13, 68, and 3 nM, respectively[1].
- SMILESO=C(C(C1=CC(N2CCN(C(C(C)(O)C)=O)CC2)=CC=C1C(F)(F)F)=C3C4=CNC5=C4C=CC=C5)NC3=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![TCS 21311 [1260181-14-3]](https://www.targetmol.com/group3/M00/36/12/CgoaEGayNsiEYar3AAAAAGSnp3M800.png)