WB analysis of SK-N-SH cell lysate using GTX85177 TCTN2 antibody. Working concentration : 1 microg/ml
WB analysis of SK-N-SH cell lysate using GTX85177 TCTN2 antibody. Working concentration : 1 microg/ml
TCTN2 antibody
GTX85177
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetTCTN2
Overview
- SupplierGeneTex
- Product NameTCTN2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID79867
- Target nameTCTN2
- Target descriptiontectonic family member 2
- Target synonymsC12orf38; JBTS24; MKS8; TECT2; tectonic-2
- HostRabbit
- IsotypeIgG
- Protein IDQ96GX1
- Protein NameTectonic-2
- Scientific DescriptionTCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203