WB analysis of HeLa cell lysate using GTX85175 TCTN3 antibody. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of HeLa cell lysate using GTX85175 TCTN3 antibody. Working concentration : (A) 1 and (B) 2 microg/ml
TCTN3 antibody
GTX85175
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTCTN3
Overview
- SupplierGeneTex
- Product NameTCTN3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 4 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID26123
- Target nameTCTN3
- Target descriptiontectonic family member 3
- Target synonymsC10orf61; JBTS18; OFD4; TECT3; tectonic-3
- HostRabbit
- IsotypeIgG
- Protein IDQ6NUS6
- Protein NameTectonic-3
- Scientific DescriptionTCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203