TD-0212 [1073549-10-6]

MedChem Express

TD-0212 [1073549-10-6]

10

1073549-10-6

Research Use Only

C28H34FN3O4S

527.65

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1].

OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([C@H](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O

12352200