TD-0212 (TFA) [1073549-11-7]

MedChem Express

TD-0212 (TFA) [1073549-11-7]

10

1073549-11-7

Research Use Only

98.44

C30H35F4N3O6S

641.67

TD-0212 TFA is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1].

OC(C(F)(F)F)=O.OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([C@H](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O

-20°C

12352200