TDI-11861 [2857049-72-8]

MedChem Express

TDI-11861 [2857049-72-8]

10

2857049-72-8

Research Use Only

99.35

C22H25ClF2N6O3

494.92

TDI-11861 is an orally active soluble sAC inhibitor optimized and designed based on TDI-10229 (HY-132298), with an IC50 of 3.3 nM and a KD of 1.4 nM. TDI-11861 has advantages such as high affinity, slow dissociation, and good pharmacokinetics. TDI-11861 can be used for research on male contraception and related sAC pharmacology[1][2].

NC1=NC(C2=NN(C=C2CC3=C(C=CC=C3)OCCN4CCOC[C@H]4CO)C(F)F)=CC(Cl)=N1

-20°C,2°C to 8°C

12131703