Western blot All lanes: Tyrosyl-DNA phosphodiesterase 1 antibody at 8ug/ml Lane 1: MCF-7 whole cell lysate Lane 2: Mouse lung tissue Lane 3: Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 69, 42 kDa Observed band size: 69 kDa

TDP1 Antibody

CSB-PA023352ESR1HU

ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetTDP1

Overview

Supplier
Cusabio
Product Name
TDP1 Antibody
Delivery Days Customer
20
Applications
ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID55775
Target name
TDP1
Target description
tyrosyl-DNA phosphodiesterase 1
Target synonyms
tyrosyl-DNA phosphodiesterase 1, tyr-DNA phosphodiesterase 1
Host
Rabbit
Isotype
IgG
Protein IDQ9NUW8
Protein Name
Tyrosyl-DNA phosphodiesterase 1
Scientific Description
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3-phosphodiester bond, giving rise to DNA with a free 3 phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3-phosphoglycolates on protruding 3 ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3exonuclease activity and can remove a single nucleoside from the 3end of DNA and RNA molecules with 3hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3phosphate.
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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TDP1 Antibody

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