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Western Blot Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, K562 whole cell lysate All lanes: TEAD4 antibody at 2.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 35, 45 kDa Observed band size: 49 kDa
Western Blot Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, K562 whole cell lysate All lanes: TEAD4 antibody at 2.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 35, 45 kDa Observed band size: 49 kDa
Western Blot Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, K562 whole cell lysate All lanes: TEAD4 antibody at 2.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 35, 45 kDa Observed band size: 49 kDa

TEAD4 Antibody

CSB-PA618010LA01HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetTEAD4
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Overview

  • Supplier
    Cusabio
  • Product Name
    TEAD4 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7004
  • Target name
    TEAD4
  • Target description
    TEA domain transcription factor 4
  • Target synonyms
    EFTR-2; hRTEF-1B; related transcription enhancer factor 1B; RTEF1; TCF13L1; TEA domain family member 4; TEF3; TEF-3; TEFR-1; transcription factor 13-like 1; transcription factor RTEF-1; transcriptional enhancer factor 1-related; transcriptional enhancer factor 3; transcriptional enhancer factor TEF-3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15561
  • Protein Name
    Transcriptional enhancer factor TEF-3
  • Scientific Description
    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC enhansons (5-GTGGAATGT-3) and activates transcription. Binds to the M-CAT motif.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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