Tefinostat

MedChem Express

Tefinostat [914382-60-8]

10

914382-60-8

Research Use Only

99.65

C28H37N3O5

495.61

Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias [1] .

O=C(OC1CCCC1)[C@H](C2=CC=CC=C2)NCC3=CC=C(NC(CCCCCCC(NO)=O)=O)C=C3

-20°C,2°C to 8°C

12352200