Bio-Connect

Tegaserod [145158-71-0]

HY-14153
MedChem Express
CAS Number145158-71-0
Product group Chemicals
Estimated Purity99.89
Molecular Weight301.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tegaserod [145158-71-0]
  • Delivery Days Customer
    5
  • CAS Number
    145158-71-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C16H23N5O
  • Molecular Weight
    301.39
  • Scientific Description
    Tegaserod is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research[1][2][3].
  • SMILES
    COC1=CC=C(NC=C2/C=N/NC(NCCCCC)=N)C2=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200