Tegaserod [145158-71-0]
HY-14153
CAS Number145158-71-0
Product group Chemicals
Estimated Purity99.89
Molecular Weight301.39
Overview
- SupplierMedChem Express
- Product NameTegaserod [145158-71-0]
- Delivery Days Customer5
- CAS Number145158-71-0
- CertificationResearch Use Only
- Estimated Purity99.89
- Molecular FormulaC16H23N5O
- Molecular Weight301.39
- Scientific DescriptionTegaserod is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research[1][2][3].
- SMILESCOC1=CC=C(NC=C2/C=N/NC(NCCCCC)=N)C2=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![Tegaserod [145158-71-0]](https://www.targetmol.com/group3/M00/03/23/CgoaEGY7SAiEantdAAAAAE7lQ1w843.png)