Tegaserod (maleate)
HY-14153A
Overview
- SupplierMedChem Express
- Product NameTegaserod (maleate) [189188-57-6]
- Delivery Days Customer10
- CAS Number189188-57-6
- CertificationResearch Use Only
- Estimated Purity99.90
- Molecular FormulaC20H27N5O5
- Molecular Weight417.46
- Scientific DescriptionTegaserod maleate (SDZ-HTF-919) is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod maleate has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod maleate causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod maleate has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research[1][2][3].
- SMILESO=C(O)/C=C\C(O)=O.COC1=CC=C(NC=C2/C=N/NC(NCCCCC)=N)C2=C1
- Storage Instruction2°C to 8°C
- UNSPSC12352200
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![Tegaserod maleate [189188-57-6]](https://www.targetmol.com/group3/M00/3F/47/CgoaEGc67JSEMWgmAAAAAOeOI68280.png)
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