Tegoprazan

AbMole BioScience

Tegoprazan

9

942195-55-3

Chemical

Research Use Only

C20H19F2N3O3

387.38

Tegoprazan (CJ-12420, IN-A001, K-CAB, LXI-15028) is a potassium-competitive acid blocker and a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 uM for porcine, canine, and human H+/K+-ATPases in vitro.

CN(C)C(=O)C1=CC2=C(N=C(C)[NH]2)C(=C1)OC3CCOC4=C3C(=CC(=C4)F)F

12352200