Telaprevir

MedChem Express

Telaprevir [402957-28-2]

10

402957-28-2

Research Use Only

99.65

C36H53N7O6

679.85

Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease , the steady-state inhibitory constant ( K i ) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide [1] [2] [3] . Telaprevir inhibits SARS-CoV-2 3CL pro activity [4] .

O=C(N([C@@H]1C(N[C@H](C(C(NC2CC2)=O)=O)CCC)=O)C[C@@]3(CCC[C@@]31[H])[H])[C@@H](NC([C@@H](NC(C4=NC=CN=C4)=O)C5CCCCC5)=O)C(C)(C)C

-20°C,2°C to 8°C

12352200