WB analysis of human PBMC lysate using GTX15724 TEM8 antibody, C-term. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human PBMC lysate using GTX15724 TEM8 antibody, C-term. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
TEM8 antibody, C-term
GTX15724
Overview
- SupplierGeneTex
- Product NameTEM8 antibody, C-term
- Delivery Days Customer9
- Antibody SpecificityThis antibody is expected to recognise variant 1 (NP_115584) only.
- Application Supplier NoteWB: 0.2-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID84168
- Target nameANTXR1
- Target descriptionANTXR cell adhesion molecule 1
- Target synonyms2310008J16Rik; 2810405N18Rik; anthrax toxin receptor 1; ATR; GAPO; TEM8; tumor endothelial marker 8
- HostGoat
- IsotypeIgG
- Protein IDQ9H6X2
- Protein NameAnthrax toxin receptor 1
- Scientific DescriptionThis gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203