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ProductsBack/Temozolomide [85622-93-1]
Chemical Structure
Chemical Structure
Chemical Structure

Temozolomide [85622-93-1]

Research Use Only
CDX-T0072
Chemodex
CAS Number85622-93-1
DownloadDatasheet
Product group Chemicals
Estimated Purity>98%
Molecular Weight194.15
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Overview

  • Supplier
    Chemodex
  • Product Name
    Temozolomide [85622-93-1]
  • Delivery Days Customer
    10
  • CAS Number
    85622-93-1
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger
  • Molecular Formula
    C6H6N6O2
  • Molecular Weight
    194.15
  • Scientific Description
    Chemical. CAS: 85622-93-1. Formula: C6H6N6O2. MW: 194.15. Temozolomide is a DNA methylating agent and drug resistance-modifying agent with antitumor and antiangiogenic properties. Temozolomide induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA and interfering with DNA replication and leading to cytotoxicity in proliferating cells. It has been shown to induce autophagy in malignant glioma cells. It is effective in a variety of types of cancer, including aggressive brain cancers. - Temozolomide is a DNA methylating agent and drug resistance-modifying agent with antitumor and antiangiogenic properties. Temozolomide induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA and interfering with DNA replication and leading to cytotoxicity in proliferating cells. It has been shown to induce autophagy in malignant glioma cells. It is effective in a variety of types of cancer, including aggressive brain cancers.
  • SMILES
    O=C1N(C)N=NC2=C(C(N)=O)N=CN21
  • Storage Instruction
    2°C to 8°C,RT
  • UNSPSC
    12352200