Temozolomide [85622-93-1]

MedChem Express

Temozolomide [85622-93-1]

10

85622-93-1

Research Use Only

99.98

C6H6N6O2

194.15

Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].

O=C(C1=C(N2C=N1)N=NN(C)C2=O)N

-20°C

41115800