TENC1 antibody [C2C3], C-term
GTX108618
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse
TargetTNS2
Overview
- SupplierGeneTex
- Product NameTENC1 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID23371
- Target nameTNS2
- Target descriptiontensin 2
- Target synonymsC1 domain-containing phosphatase and tensin homolog; C1TEN; C1-TEN; TENC1; tensin like C1 domain containing phosphatase (tensin 2); tensin-2; tensin-like C1 domain-containing phosphatase
- HostRabbit
- IsotypeIgG
- Protein IDQ63HR2
- Protein NameTensin-2
- Scientific DescriptionThe protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tensin2 is important for podocyte-glomerular basement membrane interaction and integrity of the glomerular filtration barrier. Uchio-Yamada K et al., 2020 Jun 1, Am J Physiol Renal PhysiolRead more
- Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways. Jeong H et al., 2017 Dec 19, Sci RepRead more
- Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation. Koh A et al., 2014 Nov, Cell SignalRead more