ProductsBack/TENC1 antibody [C2C3], C-term

TENC1 antibody [C2C3], C-term

Name: TENC1 antibody [C2C3], C-term
SKU: GTX108618_G10
Availability: BackOrder

GTX108618

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Product group Antibodies

TargetTNS2

Overview

Supplier
GeneTex
Product Name
TENC1 antibody [C2C3], C-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID23371
Target name
TNS2
Target description
tensin 2
Target synonyms
C1-TEN, C1TEN, TENC1, tensin-2, C1 domain-containing phosphatase and tensin homolog, tensin like C1 domain containing phosphatase (tensin 2), tensin-like C1 domain-containing phosphatase
Host
Rabbit
Isotype
IgG
Protein IDQ63HR2
Protein Name
Tensin-2
Scientific Description
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Uchio-Yamada K, Yasuda K, Monobe Y, et al. Tensin2 is important for podocyte-glomerular basement membrane interaction and integrity of the glomerular filtration barrier. Am J Physiol Renal Physiol. 2020,318(6):F1520-F1530. doi: 10.1152/ajprenal.00055.2020
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Jeong H, Koh A, Lee J, et al. Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways. Sci Rep. 2017,7(1):17777. doi: 10.1038/s41598-017-18081-8
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Koh A, Park D, Jeong H, et al. Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation. Cell Signal. 2014,26(11):2470-80. doi: 10.1016/j.cellsig.2014.07.033
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