Tenovin-6

MedChem Express

Tenovin-6 [1011557-82-6]

10

1011557-82-6

Research Use Only

98.33

C25H34N4O2S

454.63

Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC 50 s of 21 microM, 10 microM, and 67 microM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH) [1] [2] .

O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2

-20°C,2°C to 8°C

12352200