Tenuazonic acid

MedChem Express

Tenuazonic acid [610-88-8]

10

610-88-8

Research Use Only

99.58

C10H15NO3

197.234

Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer[1][2][3][4][5][6][7].

O=C1N[C@@H]([C@@H](C)CC)C(O)=C1C(C)=O

2°C to 8°C

12352200