Teprotumumab [1036734-93-6]
HY-P99165
Product group Antibodies
Overview
- SupplierMedChem Express
- Product NameTeprotumumab [1036734-93-6]
- Delivery Days Customer10
- CAS Number1036734-93-6
- CertificationResearch Use Only
- ClonalityMonoclonal
- Estimated Purity99.46
- Scientific DescriptionTeprotumumab is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular alpha-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research[1].
- Storage Instruction-80°C
- UNSPSC41116161