Teprotumumab
M24540
Product group Antibodies
Overview
- SupplierAbMole BioScience
- Product NameTeprotumumab
- Delivery Days Customer9
- Category SupplierAntibody
- CertificationResearch Use Only
- Scientific DescriptionTeprotumumab (RV001, R1507) is a first-in-class IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular alfa-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research.
- Storage InstructionPlease store the product under the recommended conditions in the Certificate of Analysis.
- UNSPSC12352203