Teprotumumab
ORB1980716
Product group Antibodies
Overview
- SupplierBiorbyt
- Product NameTeprotumumab
- Delivery Days Customer10
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration2.74 mg/ml
- ConjugateUnconjugated
- Estimated Purity99.6%
- Scientific DescriptionTeprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular alpha-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-associated eye diseases.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203