Bio-Connect

Teprotumumab

ORB1980716
Biorbyt
Product group Antibodies
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Teprotumumab
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    2.74 mg/ml
  • Conjugate
    Unconjugated
  • Estimated Purity
    99.6%
  • Scientific Description
    Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular alpha-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-associated eye diseases.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203