Terreic acid [121-40-4]

BioViotica

Terreic acid [121-40-4]

10

121-40-4

Research Use Only

>99%

Warning

C7H6O4

154.1

Chemical. CAS: 121-40-4. Formula: C7H6O4. MW: 154.1. Isolated from Aspergillus terreus.. Mycotoxin. Antibacterial and anticancer agent. A cell-permeable quinone epoxide antibiotic. Covalent inhibitor of the bacterial enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA), which catalyzes the first committed step of bacterial cell wall biosynthesis. More potent than the known MurA inhibitor Fosphomycin. Reversible, substrate competitive and selective inhibitor of Brutons tyrosine kinase (BTK) catalytic activity, an important factor in B-cell and mast cell activation. Shown to bind to the BTK pleckstrin homology domain (BTK-PH) and block the interaction between the BTK-PH and PKC, affecting the catalytic activity of BTK but not of PKC. Has minimal effect on Lyn, Syk, PKA, casein kinase I, ERK1, ERK2, and p38 kinase activities. Antioxidant. - Mycotoxin. Antibacterial and anticancer agent. A cell-permeable quinone epoxide antibiotic. Covalent inhibitor of the bacterial enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA), which catalyzes the first committed step of bacterial cell wall biosynthesis. More potent than the known MurA inhibitor Fosphomycin. Reversible, substrate competitive and selective inhibitor of Brutons tyrosine kinase (BTK) catalytic activity, an important factor in B-cell and mast cell activation. Shown to bind to the BTK pleckstrin homology domain (BTK-PH) and block the interaction between the BTK-PH and PKC, affecting the catalytic activity of BTK but not of PKC. Has minimal effect on Lyn, Syk, PKA, casein kinase I, ERK1, ERK2, and p38 kinase activities. Antioxidant.

O=C([C@@H]1[C@H]2O1)C(C)=C(O)C2=O

-20°C,2°C to 8°C

12352200