Chemical Structure
Territrem B [70407-20-4]
AG-CN2-0142
Overview
- SupplierAdipoGen Life Sciences
- Product NameTerritrem B
- Delivery Days Customer10
- ADR Class6.1
- CAS Number70407-20-4
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationDanger,Excepted quantity
- Molecular FormulaC29H34O9
- Molecular Weight526.6
- Scientific DescriptionChemical. CAS: 70407-20-4. Formula: C29H34O9. MW: 526.6. Synthetic. Originally isolated from Aspergillus terreus. Tremorgenic mycotoxin. Potent and specific, irreversible acetylcholinesterase (AChE) inhibitor. - Tremorgenic mycotoxin [1, 2]. Potent and specific, irreversible acetylcholinesterase (AChE) inhibitor [3-7].
- SMILESCOC1=CC(=CC(OC)=C1OC)C1=CC2=C(C[C@@]3(O)[C@@](C)(CC[C@@]4(O)C(C)(C)C=CC(=O)[C@]34C)O2)C(=O)O1
- Storage Instruction-20°C,2°C to 8°C
- UN NumberUN 3462
- UNSPSC12352200
References
- Territrems, tremorgenic mycotoxins of Aspergillus terreus: K.H. Ling, et al.; Appl. Environ. Microbiol. 37, 355 (1979)
- Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem B' from Aspergillus terreus: F.C. Peng, et al.; Appl. Environ. Microbiol. 49, 721 (1985)
- Effects of territrem-B on cholinergic responses of snail neuron: V.L. Arvanov, et al.; Neurosci. Lett. 152, 69 (1993)
- Acetylcholinesterase inhibition by territrem B derivatives: F.C. Peng; J. Nat. Prod. 58, 857 (1995)
- Territrems: Naturally Occurring Specific Irreversible Inhibitors of Acetylcholinesterase: J.W. Chen & K.H. Ling; J. Biomed. Sci. 3, 54 (1996)
- Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. I. Screening, taxonomy, fermentation, isolation and biological activity: F. Kuno, et al.; J. Antibiot. 49, 742 (1996)
- Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism: J.W. Chen, et al.; J. Biol. Chem. 274, 34916 (1999)